Gilson Preparative HPLC System

Gilson Preparative HPLC System

Modular and robust prep HPLC platforms configured to your requirements.

Preparative HPLC systems in a modular format to accommodate purification ranging from a microgram to gram scale utilizing UV, ELSD, DAD, and/or MS as a fraction trigger and valve configurations to accommodate virtually any number of single or multiple column schemes.


The systems’s wide flow rate range (from the 333 and 334 Pumps) allows for both semi-preparative and preparative separations. High pumping power accommodates a wide range of preparative column sizes. All injection modules feature a continuous flow path design. The system can accommodate large injection volumes with minimal sample waste and carryover. The new rinse station system incorporates a flowing jet wash and allows the use of up to two different rinse solvents.

  • Low dwell volume allows fast, reproducible gradients
  • Off bed collection racks allow for true large-scale fraction collection into vessels of your choice without sacrificing bed space
  • Incorporate Gilson’s System Organizers for stacking to conserve bench space
  • Injection of up to 15 g per run depending on column dimensions
  • The 30X Pump Series configured as injection pumps can inject volumes up to several liters to maximize sample loading on preparative HPLC columns
  • Separate injection and collection pathways that eliminate contamination of fractions from the injection process
  • The solvent valve allows for immediate access of up to five off bed solvent reservoirs
  • The GX Direct Injection Module features an innovative injection port design that attaches directly to the injection valve reducing void volumes
  • and minimizing carryover associated with calibrated connection tubing
  • The GX Direct Injection Module offers various sample loop sizes providing the largest sample volume range on the market today


  • Sample Loading Capacity Up to 15 g/injection
  • Optimal Column Size 10–100 mm
  • Flow Rate 2.0–200 mL/min
  • Maximum Injection Pressure 5,000 psi (345 bar)
  • Maximum Pump Pressure 3,040 psi (210 bar)

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