Cell Culture Supplements
Advanced cell culture supplements, designed for accelerated and assured CLD workflows
Reagents for enhanced seeding and accelerated cell growth
Solentim’s technologies combine their technical expertise with an in-depth knowledge of cell creation, isolation, analysis and documentation to manage high value cells from discovery to production. Solentim’s enabling reagents and unparalleled domain expertise transform the speed and efficiency of clonally-derived Master Cell Bank development. Introducing Solentim’s MatriClone™, an imaging ready seeding matrix for iPSC cells, and InstiGRO™, a powerful growth supplement for CHO and HEK cells.
InstiGRO, InstiSHAKE™ and InstiTHAW™
enhancing cell line development workflows
In the search for high-value cells, growth conditions can be optimised to support early growth conditions. InstiGRO products are proprietary animal component-free cell culture supplements for CHO and HEK cells which confer major growth and survival advantages within cell line development.
Designed to work with VIPS automation, Cell Metric imaging or manual cell practices, InstiGRO can transform workflows with greatly enhanced successful colonies per plate.
The range of supplements is designed to enhance growth at different stages of cell line development for accelerated workflows:
A NEW STANDARD FOR IPSC SUPPORT WITH MATRICLONE iPSC MATRIX
Soluble matrix for high efficiency, high viability iPSC single cell cloning and outgrowth
MatriClone is a new matrix designed to support iPSC growth in single seeding workflows while maintaining pluripotency. MatriClone is a defined matrix consisting of a recombinant peptide and is animal component-free. MatriClone is optimised for ‘in-solution’ seeding and optically suited for automated imaging. When used as part of the VIPS seeding protocol, MatriClone offers high levels of single cell survival and subsequent outgrowth, all in a simple, automated workflow which avoids the need for coating plates.
Designed for use with automated imaging
Maintenance of phenotype, karyotype and pluripotency
Importantly, clones generated using the VIPS + MatriClone workflow have been shown by immunocytochemistry and karyotyping to maintain pluripotency after at least 10 passages and have retained their ability to successfully differentiate.
Cell Line Developement
Solentim’s InstiGRO and MatriClone cell culture supplements are specifically designed to work with VIPS automation, Cell Metric imaging or manual cell practices to transform cell line development workflows, with greatly enhanced successful colonies per plate.
Cell line development for biotherapeutics
Generate stable cell lines that create producing novel recombinant proteins such as monoclonal antibodies or therapeutic proteins for rare diseases
SINGLE CELL CLONING OF hiPSCs
High efficiency, high viability single cell cloning of hiPSCs for applications including development of disease models and supporting GMP manufacture of cell therapies
Virus manufacturing for gene therapy
From the selection of high producer clones to the development of stable vector producer cell lines, explore our simplified workflows for gene therapy applications
Cell engineering and precision gene editing
Optimise your drug discovery process using targeted gene editing to create stable cell lines as cellular reagents, for use in target validation, functional genomics and disease modelling
Vaccine production with mammalian cells
Isolate, screen and characterise attributes for clones producing novel recombinant sub-unit protein and monoclonal antibody vaccines
Engineered exosome producer cell lines
Establish stable producer cells for the production of engineered and cell-engineered exosomes
InstiGRO, InstiSHAKE and InstiTHAW
Advanced cell culture supplements for use with CHO and HEK cellsA range of advanced animal-free cell growth supplements for use with CHO and HEK cells designed to enhance growth at different stages of cell line development for superior workflows
MatriClone matrix for iPSC
Soluble matrix for high efficiency, high viability iPSC single cell cloning and outgrowthStem cell matrix for use ‘in-solution’ during single cell seeding with the VIPS system to support early growth
About Solve Scientific
Solve Scientific caters to the Australian and New Zealand scientific market with high-quality product and innovative technologies. In close partnership with our suppliers our role is delivering premium local support in enabling our customer’s results.