Applications
Cell Line Development
Solutions to accelerate the cell line development workflow with technologies for:
- Single cell seeding and monoclonality assurance
- Bioprocess titre and impurity testing, process development and QC
Enhancing cell line development workflows with our partners Solentim and FortéBio
FortéBio’s Octet systems, based on biolayer interferometry (BLI) technology enable label-free biologic characterisation for bioprocess titre and impurity testing, process development and quality control. BLI characterisation of biologics provides critical information for specificity and affinity of biomolecular interactions to monitoring concentration and Critical Quality Attributes during cell line development and bioprocessing workflows.
Monoclonality assurance tools streamlining CLD workflows
Smarter workflows for future medicines
Solentim accelerates cell line workflow timelines from upstream development through scale-up to production of new biological therapies. From vector design and host cell selection prior to transfection, single-cell cloning and colony outgrowth right through to the establishment of the Master Cell Bank, Solentim technologies provide the evidence for credible IND submissions.
Solentim’s platforms and reagents support the following CLD workflows:
- Biotherapeutic, vaccine and exosome manufacture
- hiPSCs for stem cell therapies
- Viral vector manufacture for gene therapy
- Cell engineering for drug discovery
Biolayer interferometry (BLI) advancing CLD workflows
Industry standards for label-free analysis of biomolecular interactions
BLI characterisation of biologics provides critical information for specificity and affinity of biomolecular interactions to monitoring concentration and Critical Quality Attributes during cell line development and bioprocessing workflows.
FortéBio’s Octet systems accelerate the cell line development workflow by providing fast, reliable quantitation, even in crude samples. Rapidly screen clone libraries to isolate high producing clones, monitor product quality and titre through the manufacture process, and qualify your biologic lot-to-lot. With Octets, you can perform:
- Clone screening
- Titre and impurity monitoring
- Product development and QC
- GxP applications
About Solve Scientific
Solve Scientific caters to the Australian and New Zealand scientific market with high-quality product and innovative technologies. In close partnership with our suppliers our role is delivering premium local support in enabling our customer’s results.