Gilson
PLC purification systems
All-in-one preparative HPLC, Flash chromatography and CPC
Flexible and high performance
liquid chromatography
With the capability to purify compounds by preparative HPLC, CPC and flash chromatography on the same instrument, Gilson’s PLC purification systems simplify and streamline compound purification. These customisable instruments are available in simple configurations for basic applications, but with a wide range of upgrade options to meet your lab’s demands.

Classic HPLC to flash to CPC
Easily switch from preparative to flash chromatography with a simple column change. Connect to a Gilson CPC system for complete, fully automated CPC purification.
Smart design for maximised performance
These compact systems feature UV/VIS detection, an integrated pumping system, fraction collector, touchscreen control, and Gilson Glider Prep software.
Easy to use
PLC systems feature an intuitive touchscreen interface for easy method writing and modifying of parameters.

Features
Increase your purification throughput
Versatile to perform advanced purification protocols
PLC systems contain a variable dynamic mixing chamber and feature two or four independent solvent inlets for binary or quaternary gradients.
Detection options
PLC systems include a conductivity / pH monitor and four-wavelength UV/VIS detection, with an optional upgrade to a diode array detector (DAD) or evaporative light scattering detection (ELSD).
Large capacity for a variety of applications
PLC systems have a large fraction capacity, containing a three-rack fraction collector with unlimited collection cycles. These systems support purification from 10 – 100 mm HPLC columns, 100 – 1000 mL CPC columns and 2.5 g – 1.2 Kg flash cartridges.
Intelligent integrated pumping
PLC systems feature a dual reciprocating pump technology, with a built-in automatic injection valve.

Download brochures for more information:
Systems

PLC 2050
Low-capacity system
Compact system that is well-suited for research scale purifications

PLC 2250
Moderate-capacity system
Versatile purification system with higher-throughput and capacity

PLC 2500
High-capacity system
With a flow rate of up to 500 mL/min, perform large scale purifications with ease
Specifications
PLC 2050 | PLC 2250 | PLC 2500 | |
---|---|---|---|
Flow rate range | 1 - 50 mL/min | 5 - 250 mL/min | 10 - 500 mL/min |
Maximum pressure | 300 bar | 230 bar | 110 bar |
Preparative HPLC column diameter | 10 – 30 mm | 10 – 50 mm | 20 – 100 mm |
Flash chromatography cartridges | 2.5 – 70 g | 10 – 600 g | up to 1.2 kg |
Compatible CPC column sizes 100 mL 250 mL 1000 mL |
Yes Yes - |
- Yes* Yes |
- - Yes* |

About Solve Scientific
Solve Scientific caters to the Australian and New Zealand scientific market with high-quality product and innovative technologies. In close partnership with our suppliers our role is delivering premium local support in enabling our customer’s results.