Cell Metric Systems
Benchtop high-resolution whole well imaging
Providing dedicated, purpose-designed, high-resolution whole-well imaging for daily recording of clonal outgrowth in cell line development
The trusted standard for clonal assurance
Cell Metric captures a timeline of high quality whole well imaging as solid evidence of clonal origin. Unmatched high clarity imaging designed for single cell detection, even if the cell is at the wall edge
Such is the confidence in data originating from the Cell Metric, workflows, such as those involving sub-cloning, mini-pools or repeated limited dilution rounds, can be significantly compressed.
Cell Metric wraps up the story including imaging, time stamps, annotation and comments as a solid record of evidence ready for confident IND submission.
Evidence that it started as a single cell
Daily Whole Well Imaging
Cell Metric combines high quality images with data continuity, providing daily imaging with recorded evidence of single-cell to clonal growth.
High Resolution Images
Specialised, high quality images enable the user to observe and clearly annotate single cells. Single cells are discriminated from doublets and wells not containing cells.
Purpose-built for imaging assurance
Right up to the edge
Solid evidence comes from clear single cell images. Sophisticated methodologies to maintain image clarity right up to the edge.
Clarity in purpose
Designed specifically for the needs of assurance of clonality, Cell Metric has a highly tuned brightfield optical path that maximises the clarity of single-cell imaging for assured cell line development.
Automated confluence determination
For the effective tracking of daily outgrowth, Cell Metric offers automatic measurement and reporting of confluency.
Always in focus
To manage variation across multi-well plates, proprietary laser focussing ensures optimal focal position in each and every well.
Fluorescence imaging for rare event detection
As a tool for workflow verification, Cell Metric offers the option of rapid rare-event fluorescent imaging and reporting.
An audit of cell history
Combine data from the entire timeline into a documented clonality report.
Cell Line Development
Cell Metric systems are specifically designed for providing monoclonality assurance in cell line development, with high clarity whole well imaging.
Cell line development for biotherapeutics
Generate stable cell lines that create producing novel recombinant proteins such as monoclonal antibodies or therapeutic proteins for rare diseases
SINGLE CELL CLONING OF hiPSCs
High efficiency, high viability single cell cloning of hiPSCs for applications including development of disease models and supporting GMP manufacture of cell therapies
Virus manufacturing for gene therapy
From the selection of high producer clones to the development of stable vector producer cell lines, explore our simplified workflows for gene therapy applications
Cell engineering and precision gene editing
Optimise your drug discovery process using targeted gene editing to create stable cell lines as cellular reagents, for use in target validation, functional genomics and disease modelling
Vaccine technology and production with mammalian cells
Isolate, screen and characterise attributes for clones producing novel recombinant sub-unit protein and monoclonal antibody vaccines
Engineered exosome producer cell lines
Establish stable producer cells for the production of engineered and cell-engineered exosomes
Cell Metric CLD
Cell Metric® CLD is our premium version of the Cell Metric with a factory built-in, incubated plate loader for unattended imaging of 10 plates in a cassette.
Cell Metric is part of a portfolio of products along with the VIPS for cell line development. Once the single cells are in the wells, then Cell Metric can be used to monitor the outgrowth, expansion and other key metrics in making choices of best clones to take forwards.
About Solve Scientific
Solve Scientific caters to the Australian and New Zealand scientific market with high-quality product and innovative technologies. In close partnership with our suppliers our role is delivering premium local support in enabling our customer’s results.